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In addition to its role in energy production via the TCA cycle, -KG plays a central role in amino acid synthesis, redox balance, and the regulation of cell signaling

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Studies by Greenwood-Van Meerveld and colleagues using rodent POI models demonstrated that ipamorelin produced dose-dependent improvements in gastric emptying and reversal of POI-induced delayed gastrointestinal transit, with effects mediated through GHS-R1a expressed in gastrointestinal smooth muscle and enteric nervous system tissue

Epithalon supplied for research applications is typically manufactured to high purity standards and is characterized as an LPS-free peptide , endotoxin-free peptide , and research peptide endotoxin tested to ensure suitability for sensitive laboratory assays, cellular studies, and biochemical analysis